Materials and methods this prospective clinical trial included 35 infertile men with varicocele randomly divided into control (n=20) and nac (n=15) groups. Study characteristics and quality the characteristics of the 5 selected studies are presented in table table1 1the dataset includes 564 patients with a diagnosis of ipf, 286 patients in the n-acetylcysteine group and 278 patients in the control groupthe quality scores of each study included in the analysis were assessed using the cochrane risk of bias tool 18 and are described in table.
During this study, individuals with varicocele were randomly assigned to control (non-nac) and nac groups in order to show that there were no significant differences between the two groups before treatments, the sperm parameters between control and nac groups were compared.
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